Phenytoin package insert

Complete your Roto Grip collection with grip sacks, towels and more.Dermatological manifestations sometimes accompanied by fever have included scarlatiniform or morbilliform rashes.Seizure Prophylaxis During or Following Neurosurgery Dilantin, phenytoin, Phenytek, More. 2 more conditions.A fall in plasma levels may occur when patients are changed from oral to intramuscular administration.

Patients stabilized on a daily oral regimen of phenytoin experience a drop in peak blood levels to 50 to 60 percent of stable levels if crossed over to an equal dose administered intramuscularly.There is a relatively small margin between full therapeutic effect and minimally toxic doses of this drug.Dizziness, insomnia, transient nervousness, motor twitchings and headaches have also been observed.Although not a true drug interaction, tricyclic antidepressants may precipitate seizures in susceptible patients and phenytoin dosage may need to be adjusted.You can get all the info you need about health problems solutions.Other more serious forms which may be fatal have included bullous, exfoliative or purpuric dermatitis, lupus erythematosus, Stevens-Johnson syndrome, and toxic epidermal necrolysis (see PRECAUTIONS ).

These have included thrombocytopenia, leukopenia, granulocytopenia, agranulocytosis and pancytopenia with or without bone marrow suppression.

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Phenytoin: MedlinePlus Drug Information

Loss of posttetanic potentiation prevents cortical seizure foci from detonating adjacent cortical areas.Phenytoin is an anticonvulsant which may be useful in the treatment of status epilepticus of the grand mal type.Ingestion times of phenytoin and antacid preparations containing calcium should be staggered in patients with low serum phenytoin levels to prevent absorption problems.

Phenytoin should be used with caution in patients with hypotension and severe myocardial insufficiency.Although resolution of symptoms may be spontaneous, skin necrosis and limb ischemia have occurred and required such interventions as fasciotomies, skin grafting and amputation.Phenytoin Sodium Injection should be injected slowly and directly into a large vein through a large-gauge needle or intravenous catheter.

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These highlights do not include all the information needed to use DILANTIN-125.

Total exchange transfusion has been used in the treatment of severe intoxication in pediatric patients.PROCARDIA XL- nifedipine tablet, film coated, extended release Pfizer Laboratories Div Pfizer Inc-----.Is dilantin extended release, dilantin brand price,. phenytoin extended release package insert.Easy to read FDA package insert, drug facts, dosage and administration, and adverse effects for Dilantin (phenytoin).A complete list of all reactions to phenytoin can be found in the package insert,.

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Intramuscular administration should not be used in the treatment of status epilepticus because the attainment of peak plasma levels may require up to 24 hours.

Where oral dosage is resumed following intramuscular usage, the oral dose should be properly adjusted to compensate for the slow, continuing IM absorption to avoid toxic symptoms.Therefore, Phenytoin Sodium Injection should be administered as described above.Individual drug package inserts should be consulted. 4182431BJH) (PHENYTOIN - UNII:6158TKW0C5) PHENYTOIN SODIUM: 50 mg in 1 mL: Inactive Ingredients: Ingredient Name.Substitutes and alternatives to Dilantin (phenytoin) for uses like Generalized seizure, Tonic-clonic seizure and Complex partial seizure.Title: Phenytoin Sodium Capsule Package Insert - Phenytoin Sodium 100mg Tablet Subject: Dilantin iv push administration, what is subtherapeutic serum dilantin level.


Serum concentrations should be monitored and care should be taken when switching a patient from the sodium salt to the free acid form.

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Dilantin Capsule Package Insert - Dilantin 125 Package Insert

It is important to note that antiepileptic drugs should not be discontinued in patients in whom the drug is administered to prevent major seizures, because of the strong possibility of precipitating status epilepticus with attendant hypoxia and threat to life.While macrocytosis and megaloblastic anemia have occurred, these conditions usually respond to folic acid therapy.For administration of phenytoin in patients who cannot take oral medication for periods greater than a week, gastric intubation may be considered.Page 3: Hospira, Inc.: Phenytoin Sodium Injection is indicated for the control of status epilepticus of the grand mal type and prevention and treatment of.